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Organic compounds that consist of nitric acid with organic functional group substitutions; includes compounds that are derived from organic nitric acids.
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Nicorandil (CAS 65141-46-0) is a small molecule that acts as a potassium channel opener and an activator of guanylate cyclase By facilitating potassium efflux nicorandil induces membrane hyperpolarization in vascular smooth muscle cells leading to vasodilation Additionally it enhances intracellular cyclic GMP (cGMP) levels through direct stimulation of guanylate cyclase subsequently activating protein kinase G (PKG) The activation of PKG results in downstream phosphorylation events that inhibit contractile processes in smooth muscle Nicorandil is widely used as a tool compound in cardiovascular research particularly in studies investigating angina vasorelaxation and cellular mechanisms of vascular tone regulation
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We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. Dimethyl isosorbide (DMI) is a biobased greener solvent and thus aligns with Use of Renewable feedstocks and Safer Solvents and Auxiliaries. Click here for more information.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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Amyl acetate is an aliphatic ester that occurs naturally in banana fruit. It may be one of the odor volatiles produced by fungi such as Aspergillus Penicillium and Fusarium species.
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Isoamyl isovalerate is an apple flavor volatile compound mainly found in apple and banana. It is used as a flavoring agent in chewing gums candies and baked goods.
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Isoamyl acetate is the major ginjo-flavor components of Japanese sake (Ginjo-shu). It is effective in inactivating various microorganisms. Synthesis of isoamyl acetate by lipase-catalyzed transesterification of ethyl acetate in n-hexane has been reported. It is flavor-active compound present in beer.
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